Kremers Urban Pharmaceuticals

Kremers Urban Pharmaceuticals

KREMERS URBAN PHARMACEUTICALS

Crothersville, Indiana

Mussett Nicholas Associates designed a $14 million R&D / QC Lab for a team of 50 employees. The facility included two labs, nine cleanroom processing units, and a full array of laboratory services including:

  • RO Water Service
  • Compressed Air
  • Clean Air
  • Nitrogen
  • House Vac
  • High-Pressure Vac
  • Variable Speed Hoods
  • Industrial Plant
  • New Construction and Expansion
  • 200,000 Square Feet

Chemistry Flexible Laboratory & Vivarium Conversion

Chemistry Flexible Laboratory & Vivarium Conversion

CHEMISTRY FLEXIBLE LABORATORY AND VIVARIUM CONVERSION

The project converted 6,300 square feet of vivarium space into 3,000 square feet of flexible laboratory space and 3,300 square feet of IWP with a break area. Flexible laboratory included 14 low-flow fume hoods and mobile casework. The project utilized a flexible utility layout with ceiling interface panels and utility distribution piping with quick disconnects.

The renovation of a 2,900-square-foot laboratory space included 2,500 square feet of open lab space and 500 square feet for a cell culture lab. Spaces were separated using a demountable wall system mounted to a service ceiling. The service ceiling is laid out in an 8’x8’ grid system, which allows for service columns and walls to be easily relocated. Building utility systems were routed in a loop with quick disconnects every 5 feet to allow for movement of service columns. Electricity was routed using a bus duct system to allow for easy relocation of electrical equipment. Energy-saving features include LED lights, low-flow fume hoods with zone presence sensors and sash monitors, and a VAV HVAC system.

  • Flexible Chemistry Lab
  • Renovation
  • 2,900 Square Feet

Medical Device Manufacturer

Medical Device Manufacturer

Medical Device Manufacturer

Crothersville, Indiana

The scope of this project included the demolition of an existing building to allow for the construction of this facility. Mussett Nicholas Associates provided the MEP design for this building, which included the consolidation of several laboratories on campus into this facility. The building was constructed within an existing campus, directly adjacent to three (3) other buildings. The building comprised BSL-2 laboratories, support spaces, material storage, environmental test chambers, and administrative areas. The building included GMP areas with temperature and humidity requirements.

MODEL:The design utilized Revit as the BIM modeling software. During design, coordination was accomplished with consultants exchanging models and the use of Navisworks for clash detection. During the construction, the various construction trades used BIM for coordination. MNA actively participated with the contractors during these coordination efforts.

MEP SYSTEMS: The building systems included:

  • Chilled Water
  • Cooling Water (for Chilled Beams)
  • Heating Water
  • Plumbing Systems
    • Potable Water
    • Sanitary
    • Storm
  • Air Handling Units with Energy Recovery
  • Desiccant Dehumidification Unit
  • Humidification
  • Chilled Beams
  • Electrical Power
  • Back-Up Generator Power
  • Telecom
  • Lighting Control System
  • Electrical Systems
    • Fire Alarm
    • Access Control
    • CCTV
    • Sound Masking
  • Compressed Air
  • High Purity Water
  • Nitrogen
  • Building Management System

SUSTAINABILITY:

  • AHUs with Energy Recovery
  • AHUs with Sensible Wheels
  • Ductwork and AHUs Designed for Low Air Velocity
  • Piping Designed for Low Water Velocity
  • Chilled Beam HVAC System to Reduce Simultaneous Heating/Cooling.
  • Lighting Control Systems with Daylight Harvesting
  • LED Lighting
  • Produced With, or Cooling Systems Utilizing, Halogenated Hydrocarbon Refrigerants Were Not Allowed

COMMISSIONING/TURN-OVER: MNA provided assistance through collaboration with a 3rd party commissioning agent during initial start-up and functional tests. In addition, MNA attended training sessions with the commissioning agent, equipment vendors, contractors, and the owner during the turnover phase of the project. This provided the owner’s facility team a complete perspective of the project compared to conventional training sessions

  • Industrial Plant
  • New Construction and Expansion
  • 200,000 Square Feet

Gas Turbine Engine Manufacturer

Gas Turbine Engine Manufacturer

GAS TURBINE ENGINE MANUFACTURER

Indianapolis, Indiana

A new test cell for development and production tests of lift fans under differing nozzle and inlet conditions. The project included a new electric utility substation to deliver 13kV power to a 40,000hp motor. Mussett Nicholas Associates was a consultant to the prime test cell facility design firm.

  • Industrial High Horsepower Test Cell
  • New Construction
  • 20,000 Square Feet

Shortridge Middle & High School

Shortridge Middle & High School

SHORTRIDGE MIDDLE & HIGH SCHOOL

Indianapolis, Indiana

Conversion of Shortridge Middle School from a Theater/Arts Magnet to a Government/Law Magnet Middle & High School. Mussett Nicholas Associates assisted Indianapolis Public Schools (IPS) in programming the facility for grades six through twelve.

Air-conditioning was added with complete upgrading of mechanical, electrical, controls, and intercom systems. A complete re-roof of the historic building was included, along with limestone restoration and masonry repairs. Installing a new kitchen was included in this project.

  • Middle School to Magnet School Conversion
  • Facility Upgrades Including
    • Air Conditioning
    • Kitchen
    • Exterior Restoration
    • Electrical System Replacement
  • 296,100 Square Feet

One Indiana Square

One Indiana Square

ONE INDIANA SQUARE

Indianapolis, Indiana

Over the life of the building, Mussett Nicholas Associates has been responsible for the following significant renovations:

  • Chiller Plant Replacement on the 36th Floor Mechanical Space
  • Conversion to Direct Variable Speed Chilled Water Loop
  • Air Handler Control Changes, Including VFD Fans and Two-Way Control Valves
  • Wet Standpipe System and Addition of Sprinkler Fire Protection
  • Numerous Tenant Renovations on Each Floor of the Building
  • 750 KVA Emergency Generator
  • ADA-Compliant Restroom Upgrades
  • New Lighting and Ceiling Standards
  • Donkey Boiler
  • Heat Recovery Systems
  • Fire Alarm Upgrade
  • Donkey Pump and Fire Pump
  • Initial VAV Box Replacements
  • New Glass Skin Mechanical Impacts
  • Commercial Office Building
  • 35 Stories
  • 70,000 Square Feet
  • Built in 1972

Hilton Garden Inn – Downtown Indianapolis

Hilton Garden Inn – Downtown Indianapolis

HILTON GARDEN INN – DOWNTOWN INDIANAPOLIS

Indianapolis, Indiana

Hilton Garden Inn purchased a Historic Office Building in Downtown Indianapolis to convert into a hotel.

Mussett Nicholas Associates designed mechanical systems for compliance with ASHRAE62 fresh ventilation standards, and air-to-air heat recovery, building exhaust, and pool room ventilation.

New building services included wet standpipes and full sprinkler protection system, emergency generator, DDC HVAC control system, fire alarm system, VAV system boxes and air handlers for the conference center and atrium, four-pipe fan and coil units for suites, lighting, electrical service, sanitary and vent piping, and domestic and cold water distribution.

MNA responsibilities included:

  • Consultant Mechanical
  • Electrical
  • Plumbing Design
  • Integrated Accessible Ceiling Plan into the Corridor Hard Ceiling Planned by the Architect to Maintain Access to Important Mechanical Systems
  • Commercial Renovation of Historical Office Building into a Hotel

University of Notre Dame ACE Building

University of Notre Dame ACE Building

UNIVERSITY OF NOTRE DAME ACE BUILDING

South Bend, Indiana

Mussett Nicholas Associates provided the mechanical, electrical, and plumbing engineering for the Notre Dame Alliance for Catholic Education Building. This project was completed using BIM modeling software.

  • Higher Education

National Starch & Chemical

National Starch & Chemical

NATIONAL STARCH AND CHEMICAL

Indianapolis, Indiana

Image, context, and scale responsiveness were key concerns in designing a two-story office and high-tech R&D and QC testing labs for a manufacturer. An atrium section with stairs and a two-entrance elevator creates a transition between the new and existing buildings on the site. Skylights enhance the office and lobby areas. Details of the new facade complement the original building.

  • Industrial Office and Visitor Lobby
  • R&D and Quality Control Lab Expansion

Purdue University Zucrow Lab

Purdue University Zucrow Lab

Zucrow-Labs-3
Zucrow-Labs-1
Zucrow-Labs-2

PURDUE UNIVERSITY ZUCROW LAB

West Lafayette, Indiana

Purdue University Zucrow High-Pressure Research Lab Air Heater Installation.

This project involved the installation of an air heater for the Purdue University Propulsion Lab to provide 150°F and 800 PSI compressed air for testing. The total cost of the project was $1.6 million.

  • Higher Education
  • High-Pressure Test Cell Upgrade
  • $1.6 Million

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